EIGHTY:20 contains a ratio of Micellar Casein (80%) to Whey (20%) naturally found in milk. The blend of anti-catabolic slow-absorbing protein (Micellar Casein) and anabolic fast-absorbing protein (Whey) was specifically formulated by reviewing new emerging and historic protein research for advanced lean muscle support.
The combination of Micellar Casein and Whey has been scientifically proven to have greater nitrogen retention than whey or micellar casein alone.
It’s a common misconception fueled by product marketing that whey should only be consumed post workout and micellar casein only around bedtime. Understand that this is not an accurate representation of the facts.
Research has proven that adding micellar casein to whey will not inhibit the fast absorption of whey or the desirable slow absorption of micellar casein.
For example, leucine from whey appears in blood plasma rapidly and is associated with an increase in whole body protein synthesis during the first 180 minutes (anabolic properties) with no significant effect on protein breakdown.
To complement whey protein, micellar casein results in a slower leucine appearance in blood plasma sustained over several hours, with smaller increases in whole body protein synthesis and significant and sustained decreases in muscle protein breakdown (anti-catabolic properties). Net whole body leucine is greater after ingesting micellar casein vs. whey.
Simply put, consumed as a blend, micellar casein and whey maintain their unique slow and fast-digesting properties. For advanced lean muscle support, consume a combination of micellar casein and whey rather than either one alone.
EIGHTY:20 does not contain amino fillers or whey peptides. Whey peptides may sound cutting-edge and exciting, but they are just another amino acid-spiking trick. They artificially manipulate nitrogen protein tests, so you get less protein than for your $. Whey peptides are often incomplete proteins like glutamine peptides, glycine peptides, or a way to disguise low% whey concentration
Hoffman, J. R., & Falvo, M. J. (2004, September 1). Protein - Which is Best? Journal of sports science & medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905294/.
JE;, K. (1984). Milk proteins: physicochemical and functional properties. Critical reviews in food science and nutrition. https://pubmed.ncbi.nlm.nih.gov/6391823/.
Nakamura H;Iwamoto M;Washida K;Sekine K;Takase M;Park BJ;Morikawa T;Miyazaki Y;, N. H. I. M. W. K. S. K. T. M. P. B. J. M. T. M. Y. (2010). Influences of casein hydrolysate ingestion on cerebral activity, autonomic nerve activity, and anxiety. Journal of physiological anthropology. https://pubmed.ncbi.nlm.nih.gov/20558968/.
Rousseau-Ralliard D;Goirand F;Tardivel S;Lucas A;Algaron F;Mollé D;Robert V;Auchère D;Boudier JF;Gaillard JL;Monnet V;Tauzin J;Grynberg A;, R.-R. D. G. F. T. S. L. A. A. F. M. D. R. V. A. D. B. J. F. G. J. L. M. V. T. J. G. A. (2010). Inhibitory effect of αS1- and αS2-casein hydrolysates on angiotensin I-converting enzyme in human endothelial cells in vitro, rat aortic tissue ex vivo, and renovascular hypertensive rats in vivo. Journal of dairy science. https://pubmed.ncbi.nlm.nih.gov/20630208/.
Messaoudi M;Lefranc-Millot C;Desor D;Demagny B;Bourdon L;, M. M. L.-M. C. D. D. D. B. B. L. (2005). Effects of a tryptic hydrolysate from bovine milk alphaS1-casein on hemodynamic responses in healthy human volunteers facing successive mental and physical stress situations. European journal of nutrition. https://pubmed.ncbi.nlm.nih.gov/15517308/.
Muro Urista C;Álvarez Fernández R;Riera Rodriguez F;Arana Cuenca A;Téllez Jurado A;, M. U. C. Á. F. R. R. R. F. A. C. A. T. J. A. (2011). Review: Production and functionality of active peptides from milk. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. https://pubmed.ncbi.nlm.nih.gov/21917640/.
Hoffman JR;Ratamess NA;Tranchina CP;Rashti SL;Kang J;Faigenbaum AD;, H. J. R. R. N. A. T. C. P. R. S. L. K. J. F. A. D. (2009). Effect of protein-supplement timing on strength, power, and body-composition changes in resistance-trained men. International journal of sport nutrition and exercise metabolism. https://pubmed.ncbi.nlm.nih.gov/19478342/.
Andersen LL;Tufekovic G;Zebis MK;Crameri RM;Verlaan G;Kjaer M;Suetta C;Magnusson P;Aagaard P;, A. L. L. T. G. Z. M. K. C. R. M. V. G. K. M. S. C. M. P. A. P. (2005). The effect of resistance training combined with timed ingestion of protein on muscle fiber size and muscle strength. Metabolism: clinical and experimental. https://pubmed.ncbi.nlm.nih.gov/15690307/.
Tipton KD;Elliott TA;Cree MG;Wolf SE;Sanford AP;Wolfe RR;, K. (2004). Ingestion of casein and whey proteins result in muscle anabolism after resistance exercise. Medicine and science in sports and exercise. https://pubmed.ncbi.nlm.nih.gov/15570142/.
Pennings B;Groen B;de Lange A;Gijsen AP;Zorenc AH;Senden JM;van Loon LJ;, B. (2012). Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men. American journal of physiology. Endocrinology and metabolism. https://pubmed.ncbi.nlm.nih.gov/22338070/.
Reitelseder S;Agergaard J;Doessing S;Helmark IC;Lund P;Kristensen NB;Frystyk J;Flyvbjerg A;Schjerling P;van Hall G;Kjaer M;Holm L;, S. (2011). Whey and casein labeled with L-[1-13C]leucine and muscle protein synthesis: effect of resistance exercise and protein ingestion. American journal of physiology. Endocrinology and metabolism. https://pubmed.ncbi.nlm.nih.gov/21045172/.
D;, C. T. T. P. P. S. L. (2009). Open-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patients. Journal of gastroenterology and hepatology. https://pubmed.ncbi.nlm.nih.gov/19638084/.
Bortolotti M;Maiolo E;Corazza M;Van Dijke E;Schneiter P;Boss A;Carrel G;Giusti V;Lê KA;Quo Chong DG;Buehler T;Kreis R;Boesch C;Tappy L;, M. (2011). Effects of a whey protein supplementation on intrahepatocellular lipids in obese female patients. Clinical nutrition (Edinburgh, Scotland). https://pubmed.ncbi.nlm.nih.gov/21288612/.
S;, P. S. E. V. D. (2010). Effects of whey protein isolate on body composition, lipids, insulin and glucose in overweight and obese individuals. The British journal of nutrition. https://pubmed.ncbi.nlm.nih.gov/20377924/.